منابع مشابه
Printed in U . S . A . Biosynthesis of N - Acetyl - L - aspartic Acid
The occurrence of N-acetyl+aspartic acid in mammalian and avian brain at concentrations from 80 to 120 mg per 100 g fresh weight of tissue was demonstrated recently by Tallan et al. (1). The pattern of distribution of acetylaspartic acid in bovine brain was found by Tallan (2) to parallel that of many enzymes and to correlate equally with both the distribution of respiratory activity and the de...
متن کاملRecombinant strains of Escherichia coli for L-aspartic acid biosynthesis.
The aspartase overproducing mutant B-715 was used as a donor of the aspartase gene for further construction of the aspartase-hyperproducing strains by molecular cloning. In preliminary experiments activity of transformants and their efficiency in L-aspartic acid biosynthesis were compared. The conditions for recombinant strain multiplication, biomass activation and L-aspartic acid biosynthesis ...
متن کاملBiosynthesis of streptococcal cell walls: N-acetyl-D-muramic acid.
Glucose-1-(14)C and acetylglucosamine-1-(14)C were added singly and together with equal amounts of the unlabeled reciprocal to Brain Heart Infusion and used for the culture of Streptococcus pyogenes. The labeling pattern of the rhamnose, glucosamine, and muramic acid in the cell wall supported an intermediary role for acetylglucosamine in providing the C1-C6 moiety of muramic acid. Although rad...
متن کاملMetabolism of L-aspartic acid.
Aspartic acid, like glutamic acid, occupies a central position in amino acid metabolism. In most tissues it takes part in the transamination reaction (1). In the liver and the kidney, where all amino acids undergo cleamination, the rate of this process for aspartic acid is second only to glutamic acid (2). For these reasons, one would expect the exchange of amino nitrogen of aspartic acid with ...
متن کاملThe enzymatic synthesis of N-acetyl-L-aspartic acid by a water-insoluble preparation of a cat brain acetone powder.
An acetone powder of cat brain catalyzed the synthesis of two radioactive products when incubated with L-aspartate-14C and acetyl coenzyme A. The products were identified as Nacetyl-aspartic acid and citric acid. A water extract of the powder contained the system that produced citrate-14C, while the residue contained the aspartate N-acetyltransferase activity. The soluble system rather than the...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1959
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)69763-7